Autosomal Dominant Polycystic Kidney Disease

📋Overview

Autosomal Dominant Polycystic Kidney Disease is recognized as the most frequent inherited kidney disorder, primarily resulting from mutations in the PKD1 or PKD2 genes. This condition is passed through an autosomal dominant inheritance pattern, meaning the disorder can develop when an individual inherits a single copy of the altered gene from one parent.

As the condition progresses, the development and expansion of these cysts interfere with the kidneys' ability to filter waste from the blood. This process often causes the kidneys to become significantly enlarged, which can lead to a gradual decline in renal efficiency over time.