Duchenne Muscular Dystrophy

📋Overview

Duchenne Muscular Dystrophy is the most common form of childhood-onset muscular dystrophy and primarily affects males. This condition is caused by genetic mutations that prevent the body from producing sufficient levels of dystrophin, a protein essential for maintaining the structural integrity and stability of muscle fibers.

The absence or severe deficiency of this protein leads to the gradual breakdown of skeletal and cardiac muscles. Clinical observation shows that as muscle cells are damaged, they are progressively replaced by fat and connective tissue, resulting in a loss of functional strength.