Familial Chordoma
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📋Overview
Familial chordoma is a rare inherited form of chordoma, a slow-growing malignant tumor arising from remnants of the notochord, typically occurring along the spine or at the base of the skull. The term 'familial chordoma' refers to cases where multiple family members are affected, often linked to genetic mutations such as those in the T gene (brachyury). This distinguishes it from sporadic chordoma, which occurs without a known family history.
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