Gilbert Syndrome

📋Overview

Gilbert syndrome is a common, benign inherited condition characterized by mild, intermittent unconjugated hyperbilirubinemia due to reduced activity of the enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1). It is a genetic disorder affecting bilirubin metabolism, leading to occasional mild jaundice without liver damage. The term 'Gilbert syndrome' is the preferred modern name.