Human Cyclic Neutropenia
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📋Overview
Human cyclic neutropenia is a rare hematologic disorder characterized by regular, periodic decreases in neutrophil counts, typically occurring every 21 days. It is a form of congenital neutropenia and is most commonly caused by mutations in the ELANE gene. The condition leads to recurrent episodes of neutropenia, increasing susceptibility to infections during low neutrophil phases.
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