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๐Overview
Ohio Type Amyloidosis is a legacy term historically used to describe a form of hereditary amyloidosis characterized by amyloid deposits primarily affecting the kidneys. It is now recognized under the broader category of hereditary amyloidosis, often linked to mutations in the fibrinogen A alpha-chain gene (AFib amyloidosis). This condition leads to abnormal protein folding and amyloid fibril deposition, mainly in renal tissue, causing progressive kidney dysfunction.
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