Spinal Muscular Atrophy Type I

📋Overview

Spinal Muscular Atrophy Type I, also known as Werdnig-Hoffmann disease, is a severe genetic neuromuscular disorder characterized by progressive muscle weakness and atrophy. It is recognized as the most severe form of the condition, typically appearing within the first six months of life. Infants with this type often face significant challenges with breathing, swallowing, and motor development due to the loss of motor neurons in the spinal cord.