Thalassemia

📋Overview

This genetic condition involves a reduction or absence of specific globin chains, which are essential components of hemoglobin in red blood cells. The resulting deficiency in functional hemoglobin often leads to the destruction of red blood cells and the development of anemia.

Clinical classification typically distinguishes between alpha-thalassemia and beta-thalassemia, depending on which part of the hemoglobin molecule is affected. The severity of the condition can vary significantly based on the specific genetic mutations involved.