Question 1

What is Alogliptin?

Accepted Answer

Alogliptin belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the levels of natural substances in the body that help control blood sugar.

These substances trigger the release of insulin after eating and signal the liver to stop producing excess sugar. By supporting these natural processes, the medication helps maintain more consistent blood glucose levels.

Question 2

What is Alogliptin used for?

Accepted Answer

Alogliptin is used to treat type 2 diabetes mellitus .

Question 3

How does Alogliptin work?

Accepted Answer

Mechanism of Action

Alogliptin belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. These medications work by affecting how the body manages sugar levels, particularly after eating.

The body naturally produces hormones called incretins, such as GLP-1 (glucagon-like peptide-1). These hormones help control blood sugar in two primary ways:

Stimulating insulin: They signal the pancreas to release more insulin when blood sugar levels are high.

Reducing sugar production: They signal the liver to decrease the amount of sugar it produces and releases into the bloodstream.

Under normal conditions, an enzyme called DPP-4 quickly breaks down these incretin hormones. Alogliptin works by blocking the action of this enzyme. By preventing the breakdown of incretins, the medication allows these hormones to remain active in the body for a longer period, which helps lower blood sugar levels more effectively.

Because alogliptin works in response to the presence of sugar in the blood, it is less likely to cause dangerously low blood sugar ( hypoglycemia ) when used as a standalone treatment compared to some other diabetes medications.

Question 4

What are the brand names for Alogliptin?

Accepted Answer

Alogliptin is sold under the brand names Nesina , Kazano , and Oseni .

Question 5

What are the active ingredients in Alogliptin?

Accepted Answer

The active ingredient in Alogliptin is alogliptin .

Question 6

What are the side effects of Alogliptin?

Accepted Answer

Common side effects of Alogliptin may include:

upper respiratory tract infection

headache

nasopharyngitis

Always consult with a healthcare professional about potential side effects.

Question 7

What drug class is Alogliptin?

Accepted Answer

Alogliptin belongs to the DPP-4 inhibitor drug class.

Question 8

What is the dosage of Alogliptin and how do I take it?

Accepted Answer

How to Take This Medication

Alogliptin comes as a tablet to be taken by mouth. It is generally taken once a day. You may take this medication with or without food. To help ensure you take it consistently, try to take your dose at the same time each day.

Always follow the directions on your prescription label exactly. Do not take more or less of this medication than prescribed, and do not change your dose without consulting your healthcare provider.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and return to your regular timing. Do not take two doses at once to make up for a missed one.

Storage and Handling

Store the tablets at room temperature, away from excess heat and moisture. Keep the medication in its original container, tightly closed, and out of reach of children.

Question 9

Is Alogliptin safe during pregnancy and breastfeeding?

Accepted Answer

Pregnancy

There is limited information available regarding the safety of alogliptin in pregnant women. While animal studies have not shown evidence of harm to the fetus at high doses, there are no adequate and well-controlled studies in humans. Because animal reproduction studies are not always predictive of human response, this medication should only be used during pregnancy if clearly needed.

Maintaining stable blood sugar levels is important during pregnancy, as poorly controlled diabetes can increase the risk of complications for both the mother and the baby. Individuals who are pregnant or planning to become pregnant should discuss their treatment plan with their healthcare provider.

Breastfeeding

It is not known whether alogliptin passes into human breast milk. Because many drugs are excreted in human milk, and the effects on a nursing infant are unknown, caution should be exercised when alogliptin is administered to a person who is breastfeeding.

Healthcare providers typically evaluate the importance of the medication to the mother and the potential risks to the infant before recommending its use during breastfeeding. Patients should consult their doctor to discuss the best course of action for managing their condition while nursing.

Question 10

What forms and strengths does Alogliptin come in?

Accepted Answer

Alogliptin is provided in the following form:

Oral Tablet: A film-coated tablet intended for oral administration.

Question 11

What is the FDA approval status of Alogliptin?

Accepted Answer

FDA Approval and Indications

Alogliptin was approved by the U.S. Food and Drug Administration (FDA) as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It belongs to the dipeptidyl peptidase-4 (DPP-4) inhibitor class of medications.

Safety Communications

In 2016, the FDA issued a safety communication requiring the addition of warnings to the labels of medications containing alogliptin. This was based on clinical trial data suggesting an increased risk of heart failure, particularly in patients who already have heart or kidney disease. Healthcare providers are advised to monitor patients for signs and symptoms of heart failure after starting the medication.

Regulatory Limitations

Alogliptin is subject to the following regulatory limitations and guidance:

Type 1 Diabetes: It is not indicated for the treatment of type 1 diabetes.

Diabetic Ketoacidosis: It is not approved for the treatment of diabetic ketoacidosis.

Monitoring: The FDA recommends that patients and healthcare professionals report any side effects or heart failure symptoms, such as unusual shortness of breath, swelling in the legs or feet, or unexplained tiredness, to the FDA MedWatch program.

Question 12

What should I know about Alogliptin and cost?

Accepted Answer

Generic vs.

Brand Name

Alogliptin is available as a generic medication. Generic versions typically cost significantly less than the brand-name equivalent. Choosing the generic form is often the most direct way to lower the out-of-pocket cost for this medication.

Insurance Coverage

Most commercial insurance plans and Medicare Part D provide coverage for alogliptin. However, the amount you pay will depend on your plan's formulary. Some insurance companies may place alogliptin on a higher cost-sharing tier or require prior authorization from a healthcare provider before covering the prescription.

Pharmacy Variations

The retail price of alogliptin can vary between different pharmacies. Patients may find price differences when comparing large retail chains, independent local pharmacies, and mail-order pharmacy services. Some pharmacies also offer discount programs or savings cards that can reduce the cost for those without insurance or with high-deductible plans.

Assistance Programs

For individuals who have difficulty affording their medication, patient assistance programs may be available through manufacturers or non-profit organizations. These programs are generally based on financial need and specific eligibility requirements.

Alogliptin

📋Overview

What It's Used For

How It Works

Brand Names

Side Effects

Warnings & Precautions

Dosage & How to Take

Pregnancy & Breastfeeding

Forms & Strengths

FDA / Regulatory Status

Price Information

FAQ

Additional Resources

Support & Help Resources

📚References

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Alogliptin Price Comparison & Savings Options

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