Question 1

What is Benazepril?

Accepted Answer

Benazepril is a medication that belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. It functions by interfering with the production of certain chemicals in the body that cause blood vessels to constrict.

By promoting the relaxation of blood vessels, this medication supports improved blood flow and reduces the workload on the heart.

Question 2

What is Benazepril used for?

Accepted Answer

Benazepril is used to treat hypertension .

Question 3

How does Benazepril work?

Accepted Answer

Mechanism of Action

Benazepril belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It works by blocking the action of a specific enzyme in the body that produces a substance called angiotensin II.

Relaxing Blood Vessels

Angiotensin II is a potent chemical that causes the muscles in the walls of blood vessels to contract and narrow. When benazepril prevents the production of this substance, the blood vessels remain relaxed and open wider. This process is called vasodilation.

Effects on the Heart and Blood Pressure

By widening the blood vessels, benazepril provides several benefits for cardiovascular health:

Lower Blood Pressure: As blood vessels relax, the pressure within them decreases.

Reduced Heart Strain: The heart does not have to pump as hard to move blood through wider vessels.

Improved Blood Flow: Blood and oxygen can circulate more efficiently to the heart and other organs.

While benazepril helps control high blood pressure, it does not cure the condition. It must be taken regularly to maintain its effects on the vascular system.

Question 4

What are the brand names for Benazepril?

Accepted Answer

Benazepril is sold under the brand name Lotensin .

Question 5

What are the active ingredients in Benazepril?

Accepted Answer

The active ingredient in Benazepril is benazepril .

Question 6

What are the side effects of Benazepril?

Accepted Answer

Common side effects of Benazepril may include:

cough

dizziness

headache

and others

Always consult with a healthcare professional about potential side effects.

Question 7

What drug class is Benazepril?

Accepted Answer

Benazepril belongs to the ACE inhibitor drug class.

Question 8

What is the dosage of Benazepril and how do I take it?

Accepted Answer

Benazepril is taken by mouth, usually once or twice a day. It can be taken with or without food. It is important to take this medication at the same time each day to maintain a consistent level in your body.

Always follow the specific instructions provided by your healthcare professional or those found on your prescription label. Do not change your dose or stop taking the medication without consulting your doctor, even if you feel well.

If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take extra medicine to make up for a missed dose.

Question 9

Is Benazepril safe during pregnancy and breastfeeding?

Accepted Answer

Pregnancy

Using benazepril during the second and third trimesters of pregnancy can cause severe harm to the developing fetus. Exposure to this medication during pregnancy is associated with several serious risks, including:

Kidney failure in the newborn

Low blood pressure (hypotension)

Skull deformities

Underdeveloped lungs

Reduced amniotic fluid levels

If you become pregnant while taking benazepril, you should contact your healthcare provider immediately. In most cases, the medication must be stopped as soon as possible to protect the fetus. Your doctor can help you transition to a different blood pressure treatment that is safer for use during pregnancy.

Breastfeeding

Benazepril and its active components pass into breast milk in very small amounts. While the levels found in milk are generally considered low, the potential effects on a nursing infant are not fully understood. Healthcare providers typically advise weighing the benefits of breastfeeding against the potential risks to the infant. It is important to consult with a medical professional to determine the best course of action for your specific situation.

Question 10

What forms and strengths does Benazepril come in?

Accepted Answer

Benazepril is available as a tablet to be taken by mouth. It is used as a standalone treatment or in combination with other medications.

Common forms include:

Oral Tablet: The standard form for benazepril when used alone.

Combination Oral Tablet or Capsule: Benazepril may be combined with other blood pressure medications, such as amlodipine or hydrochlorothiazide, in a combined dosage form.

Question 11

What is the FDA approval status of Benazepril?

Accepted Answer

FDA Approval and Indications

Benazepril was first approved by the U.S. Food and Drug Administration (FDA) in 1991. It is indicated for the treatment of hypertension (high blood pressure) to lower blood pressure in adults and children aged 6 years and older. It may be used as a standalone treatment or in combination with other blood pressure medications, such as thiazide diuretics.

Boxed Warning:

Fetal Toxicity

The FDA requires a boxed warning for benazepril because drugs that act directly on the renin-angiotensin system can cause injury and even death to a developing fetus. Patients should discontinue benazepril as soon as pregnancy is detected to avoid these risks.

Safety Communications and Contraindications

The FDA has issued specific safety communications and contraindications regarding the use of benazepril:

Aliskiren: Benazepril is contraindicated for use with aliskiren in patients with diabetes. This combination should also be avoided in patients with moderate to severe renal impairment due to the increased risk of low blood pressure, high potassium levels, and changes in kidney function.

Angioedema: There is a regulatory warning regarding the risk of angioedema (severe swelling of the face, lips, tongue, or throat). The risk is higher in patients with a history of angioedema and those taking certain other medications, such as neprilysin inhibitors.

Dual Blockade: Using benazepril with other drugs that block the renin-angiotensin system is generally associated with an increased risk of hypotension, hyperkalemia, and changes in renal function.

Benazepril is available only by prescription and is not approved for over-the-counter use.

Question 12

What should I know about Benazepril and withdrawal?

Accepted Answer

Benazepril is used to manage chronic conditions like high blood pressure. It helps control these conditions but does not cure them. If you stop taking the medication, its protective effects will wear off and your blood pressure will likely rise again.

Important considerations for discontinuing benazepril include:

Medical Supervision: Do not stop taking this medication without first consulting your doctor. High blood pressure often has no symptoms, so you may not feel a difference if you stop, but your risk of heart attack or stroke may increase.

Consistency: To maintain stable blood pressure levels, the medication must be taken exactly as prescribed. Missing doses or stopping abruptly can lead to rebound hypertension.

Consultation: If you are experiencing side effects that make you want to stop the medication, talk to your healthcare provider. They can determine if a dosage adjustment or a different medication is necessary.

Benazepril

📋Overview

What It's Used For

How It Works

Brand Names

Side Effects

Warnings & Precautions

Dosage & How to Take

Pregnancy & Breastfeeding

Forms & Strengths

FDA / Regulatory Status

Withdrawal Information

FAQ

Additional Resources

Support & Help Resources

📚References

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