Question 1

What is Brilinta?

Accepted Answer

Brilinta contains the active ingredient ticagrelor and belongs to a class of drugs known as antiplatelet agents. It works by preventing platelets, which are small blood cells, from sticking together and forming clots that can block blood flow.

This medication is often referred to as a blood thinner, though it specifically targets platelet activity rather than thinning the blood itself. By maintaining consistent blood flow through the arteries, it helps reduce the risk of serious cardiovascular complications.

Question 2

What is Brilinta used for?

Accepted Answer

Brilinta is used to treat:

acute coronary syndrome

myocardial infarction

coronary artery disease

Question 3

How does Brilinta work?

Accepted Answer

Brilinta is a type of medicine called an antiplatelet drug. It works by preventing certain blood cells, called platelets, from sticking together. While clotting is a normal process that stops bleeding after an injury, it can be dangerous if clots form inside blood vessels, as they can block blood flow to the heart or brain.

Blocking Platelet Activation

The medication targets a specific receptor on the surface of platelets known as the P2Y12 receptor. Usually, a chemical in the body binds to this receptor to signal platelets to clump together. Brilinta blocks this chemical signal, which makes the platelets less sticky and reduces the risk of a heart attack or stroke in people with heart disease or those who have recently had a heart procedure.

Reversible Binding

Unlike some other antiplatelet medications that permanently affect platelets for their entire lifespan, Brilinta interacts with platelets in a reversible way. This means the effect on the platelets wears off more quickly once the medication is no longer in the system, allowing the blood's natural clotting ability to return as the drug is cleared from the body.

Question 4

What are the active ingredients in Brilinta?

Accepted Answer

The active ingredient in Brilinta is ticagrelor .

Question 5

What are the side effects of Brilinta?

Accepted Answer

Common side effects of Brilinta may include:

shortness of breath

bleeding

dizziness

and others

Always consult with a healthcare professional about potential side effects.

Question 6

What drug class is Brilinta?

Accepted Answer

Brilinta belongs to the P2Y12 receptor antagonist drug class.

Question 7

What is the dosage of Brilinta and how do I take it?

Accepted Answer

How to Take Brilinta

Brilinta is taken by mouth, usually twice every day. It is important to take the medication at the same times each day to maintain a consistent level in your body. You may take this medication with or without food.

The tablets should generally be swallowed whole with water. If you have difficulty swallowing the tablets, they can be crushed and mixed with water. After drinking the mixture, add more water to the glass, stir, and drink it immediately to ensure you receive the full dose. This medication can also be administered through a nasogastric tube by a healthcare professional.

Use with Aspirin

Brilinta is almost always taken in combination with a daily low-dose aspirin. It is critical to follow your doctor's instructions regarding the specific amount of aspirin to take, as taking too much aspirin can make Brilinta less effective.

Missed Doses

If you miss a dose, skip the missed dose and take your next dose at the regularly scheduled time. Do not take two doses at once to make up for a missed one.

Important Considerations

Do not stop taking Brilinta without consulting your healthcare provider, even if you feel well. Stopping the medication early can significantly increase your risk of having a heart attack or stroke. Ensure you have a continuous supply and refill your prescription before you run out.

Question 8

Is Brilinta safe during pregnancy and breastfeeding?

Accepted Answer

Pregnancy

There are no adequate or well-controlled studies regarding the use of Brilinta in pregnant women. In animal studies, high doses of the medication were associated with some developmental issues in the fetus, such as lower birth weight and bone variations. Because human data is limited, Brilinta should only be used during pregnancy if the potential benefit to the mother outweighs the potential risk to the unborn baby.

Breastfeeding

It is not known whether Brilinta passes into human breast milk. However, studies in animals have shown that the medication is present in the milk of lactating rats. Due to the risk of serious side effects in a nursing infant, healthcare providers typically recommend either stopping breastfeeding or stopping the medication, depending on the mother's medical needs. Patients should consult their doctor to determine the safest course of action.

Question 9

What forms and strengths does Brilinta come in?

Accepted Answer

Brilinta is supplied as a film-coated tablet intended for oral administration. These tablets are round and biconvex in shape.

For patients who have difficulty swallowing the medication whole, the tablets may be crushed and mixed with water. This mixture can be taken by mouth or administered through a nasogastric tube as directed by a healthcare provider.

Question 10

What is the FDA approval status of Brilinta?

Accepted Answer

FDA Approval and Indications

The U.S. Food and Drug Administration (FDA) has approved Brilinta (ticagrelor) for several uses related to cardiovascular health. It is indicated to reduce the rate of cardiovascular death, heart attack, and stroke in patients with acute coronary syndrome or a history of heart attack. It is also approved for use in patients with coronary artery disease who are at high risk for a first heart attack or stroke, and for certain patients who have experienced an acute ischemic stroke or high-risk transient ischemic attack (TIA).

Boxed Warnings

Brilinta carries a Boxed Warning, the FDA’s most serious type of warning, for the following risks:

Bleeding Risk: Brilinta can cause significant, and sometimes fatal, bleeding. It should not be used in patients with active pathological bleeding or a history of intracranial hemorrhage. Because it prevents clotting, it may also need to be discontinued before elective surgery.

Aspirin Dosage: The effectiveness of Brilinta is reduced when used with maintenance doses of aspirin above 100 mg daily. For patients taking Brilinta, the recommended maintenance dose of aspirin is 81 mg daily.

Safety Communications

The FDA previously issued a safety communication to address concerns regarding medication errors. There were reports of confusion between the brand name Brilinta and the antidepressant Brintellix. To reduce the risk of prescribing and dispensing errors, the manufacturer of the antidepressant changed its name to Trintellix.

The FDA also monitors the drug through the FDA Adverse Event Reporting System (FAERS). For example, the agency has previously evaluated potential signals of serious risks, such as central sleep apnea, to determine if further regulatory action or label changes were necessary based on post-marketing data.

Question 11

What should I know about Brilinta and cost?

Accepted Answer

Insurance and Generic Availability

Brilinta is a brand-name medication, and generic versions (ticagrelor) are also available. Generic drugs usually cost significantly less than their brand-name counterparts. Coverage for Brilinta varies by insurance provider and specific plan details, such as deductibles and copay tiers.

Cost Considerations

The final price a patient pays may be influenced by several factors:

Pharmacy Choice: Different pharmacies may have different retail prices for the same medication.

Assistance Programs: Financial assistance or savings programs may be available for eligible patients to help reduce out-of-pocket expenses.

Supply Quantity: The amount of medication dispensed at one time can sometimes impact the overall cost.

Patients are encouraged to consult with their pharmacist or insurance company to understand the specific costs associated with their prescription.

Brilinta

📋Overview

What It's Used For

How It Works

Side Effects

Warnings & Precautions

Dosage & How to Take

Pregnancy & Breastfeeding

Forms & Strengths

FDA / Regulatory Status

Price Information

FAQ

Additional Resources

Support & Help Resources

📚References

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