Question 1

What is Cilostazol?

Accepted Answer

Cilostazol belongs to a class of drugs known as phosphodiesterase III inhibitors . It works by widening blood vessels and preventing blood cells called platelets from sticking together, which helps to improve the flow of blood through the body.

By enhancing circulation, this medication helps to manage symptoms associated with restricted blood flow. Its general purpose is to support physical mobility and improve the quality of movement by ensuring tissues receive adequate blood supply.

Question 2

What is Cilostazol used for?

Accepted Answer

Cilostazol is used to treat intermittent claudication .

Question 3

How does Cilostazol work?

Accepted Answer

Improving Blood Flow

Cilostazol belongs to a class of medications known as phosphodiesterase III inhibitors. It works in two primary ways to help manage symptoms of poor circulation in the legs, a condition often called intermittent claudication.

Widening Blood Vessels

One of the main functions of cilostazol is vasodilation. It helps relax the smooth muscles within the walls of the arteries. When these muscles relax, the blood vessels widen, allowing blood to flow more easily through the limbs. This increased blood flow helps deliver more oxygen to the leg muscles during physical activity.

Preventing Blood Clots

Cilostazol also acts as an antiplatelet agent. Platelets are small cells in the blood that stick together to form clots. Cilostazol prevents these cells from clumping together too easily. By reducing the stickiness of platelets, the medication helps keep blood moving smoothly and lowers the risk of blockages in narrowed arteries.

Together, these actions help reduce the cramping, numbness, and pain that occur when leg muscles do not receive enough oxygen-rich blood during walking or exercise.

Question 4

What are the brand names for Cilostazol?

Accepted Answer

Cilostazol is sold under the brand name Pletal .

Question 5

What are the active ingredients in Cilostazol?

Accepted Answer

The active ingredient in Cilostazol is cilostazol .

Question 6

What are the side effects of Cilostazol?

Accepted Answer

Common side effects of Cilostazol may include:

headache

diarrhea

abnormal stools

and others

Always consult with a healthcare professional about potential side effects.

Question 7

What drug class is Cilostazol?

Accepted Answer

Cilostazol belongs to the phosphodiesterase 3 inhibitor drug class.

Question 8

What is the dosage of Cilostazol and how do I take it?

Accepted Answer

How to Take Cilostazol

Cilostazol is taken by mouth, usually twice a day. To ensure the medication is absorbed properly, it should be taken on an empty stomach. This generally means taking it at least 30 minutes before or two hours after your morning and evening meals.

It is important to take this medication at the same times every day to maintain a consistent level in your bloodstream. Follow the directions on your prescription label carefully and do not change your schedule or stop taking the medication without consulting a healthcare provider.

Missed Dose

If you miss a dose of cilostazol, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Question 9

Is Cilostazol safe during pregnancy and breastfeeding?

Accepted Answer

Pregnancy

There are no adequate and well-controlled studies of cilostazol use in pregnant women. Research in animals has shown that high doses of the medication may lead to fetal harm, including heart and skeletal abnormalities and lower birth weights. Due to these potential risks, cilostazol should only be used during pregnancy if the potential benefit to the mother outweighs the potential risk to the fetus.

Breastfeeding

It is unknown if cilostazol is excreted in human breast milk, though it has been detected in the milk of lactating animals. Because of the risk of serious adverse reactions in a nursing infant, a decision must be made whether to discontinue breastfeeding or discontinue the medication. Patients should discuss the risks and benefits with their healthcare provider to determine the best course of action.

Question 10

What forms and strengths does Cilostazol come in?

Accepted Answer

Cilostazol is available as a tablet for oral administration. It is not currently available in other dosage forms such as liquids, capsules, or injections.

Question 11

What is the FDA approval status of Cilostazol?

Accepted Answer

FDA Approval and Indications

Cilostazol was approved by the U.S. Food and Drug Administration (FDA) to improve the distance patients with intermittent claudication can walk without pain. Intermittent claudication is a condition caused by poor circulation in the legs, resulting in muscle pain or cramping during physical activity that is typically relieved by rest.

Boxed Warning

Cilostazol carries a Boxed Warning, which is the FDA's most serious warning for prescription medications. The drug is contraindicated in patients with heart failure of any severity. This warning is based on the fact that cilostazol is a phosphodiesterase III inhibitor. Other medications in this same class have been shown to decrease survival in patients with class III-IV heart failure.

Regulatory Status

Cilostazol is available as a prescription medication and is not a controlled substance. It was first approved by the FDA in 1999 and is currently available in both brand-name and generic tablet formulations.

Question 12

What should I know about Cilostazol and withdrawal?

Accepted Answer

Discontinuing Cilostazol

Cilostazol is not considered a habit-forming medication. There is no clinical evidence to suggest that it causes physical dependence or a specific withdrawal syndrome when a person stops taking it. Unlike certain other classes of drugs, it does not typically cause rebound effects or physical illness upon discontinuation.

However, patients should consider the following when stopping treatment:

Recurrence of Symptoms: Cilostazol is used to manage intermittent claudication (leg pain or cramping caused by poor circulation). If the medication is stopped, the symptoms of this underlying condition will likely return to their previous level.

Gradual Change: Because cilostazol can take several weeks to reach its full therapeutic effect, the benefits of the medication will also diminish gradually as the drug leaves the system.

Medical Consultation: It is important to speak with a healthcare provider before stopping cilostazol. They can help determine if the medication is still necessary and discuss alternative ways to manage vascular health and walking distance.

Cilostazol

📋Overview

What It's Used For

How It Works

Brand Names

Side Effects

Warnings & Precautions

Dosage & How to Take

Pregnancy & Breastfeeding

Forms & Strengths

FDA / Regulatory Status

Withdrawal Information

FAQ

📚References

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