Question 1

What is Raloxifene?

Accepted Answer

Raloxifene is a medication classified as a selective estrogen receptor modulator (SERM). It is designed to interact with estrogen receptors throughout the body, acting like the hormone estrogen in some tissues while acting against it in others.

This mechanism allows the drug to help maintain bone density and lower the risk of specific types of cancer. It provides a non-hormonal approach to managing these conditions by targeting receptors in a tissue-specific manner.

Question 2

What is Raloxifene used for?

Accepted Answer

Raloxifene is used to treat osteoporosis and to reduce the risk of invasive breast cancer .

Question 3

How does Raloxifene work?

Accepted Answer

Selective Estrogen Receptor Modulator (SERM)

Raloxifene belongs to a class of medications known as selective estrogen receptor modulators, or SERMs. This means it does not affect all tissues in the same way; it can act like estrogen in some areas of the body while acting as an anti-estrogen in others.

Bone Protection

In the skeletal system, raloxifene mimics the positive effects of estrogen. Estrogen is essential for maintaining bone strength, and when levels drop after menopause, bones can become thin and brittle. Raloxifene helps to:

Slow down the rate of bone loss.

Increase bone mineral density.

Reduce the risk of fractures, particularly in the spine.

Breast Cancer Risk Reduction

In breast tissue, raloxifene acts as an estrogen blocker. Since many breast cancers rely on estrogen to grow, blocking these signals can help prevent the development of invasive breast cancer in postmenopausal women who are at high risk.

Uterine Safety

Unlike some other hormone-related therapies, raloxifene does not stimulate the lining of the uterus. This selectivity allows it to provide bone and breast benefits without increasing the risk of uterine cancer.

Question 4

What are the brand names for Raloxifene?

Accepted Answer

Raloxifene is sold under the brand name Evista .

Question 5

What are the active ingredients in Raloxifene?

Accepted Answer

The active ingredient in Raloxifene is raloxifene .

Question 6

What are the side effects of Raloxifene?

Accepted Answer

Common side effects of Raloxifene may include:

hot flashes

leg cramps

flu-like symptoms

Always consult with a healthcare professional about potential side effects.

Question 7

What drug class is Raloxifene?

Accepted Answer

Raloxifene belongs to the Selective estrogen receptor modulator drug class.

Question 8

What is the dosage of Raloxifene and how do I take it?

Accepted Answer

How to Take Raloxifene

Raloxifene comes as a tablet to be taken by mouth. It is usually taken once a day. To help you remember to take your medication, try to take it at the same time every day.

You may take this medication with or without food. It is important to follow your healthcare provider's instructions regarding supplemental calcium and vitamin D, especially if you are taking this medication for osteoporosis. Your provider may also suggest weight-bearing exercises and lifestyle changes as part of your treatment.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take extra medicine to make up for a missed dose.

Question 9

Is Raloxifene safe during pregnancy and breastfeeding?

Accepted Answer

Pregnancy

Raloxifene is contraindicated for women who are pregnant or who may become pregnant. This medication is intended only for use by postmenopausal women. If pregnancy occurs while taking this medication, it should be discontinued immediately because it may cause harm to the developing fetus.

Breastfeeding

It is not known whether raloxifene passes into human breast milk. Because the effects on a nursing infant are unknown, breastfeeding is not recommended while using this medication. Healthcare providers typically advise against its use in individuals who are breastfeeding.

Question 10

What forms and strengths does Raloxifene come in?

Accepted Answer

Raloxifene is currently available in one primary form for administration:

Oral Tablet: This is a film-coated tablet that is swallowed whole.

The medication is typically taken once daily and can be administered regardless of food intake.

Question 11

What is the FDA approval status of Raloxifene?

Accepted Answer

FDA-Approved Indications

The U.S. Food and Drug Administration (FDA) has approved raloxifene for the following uses in postmenopausal women:

Osteoporosis: For the prevention and treatment of osteoporosis.

Breast Cancer Risk Reduction: To reduce the risk of invasive breast cancer in women who have osteoporosis or who are at high risk for developing invasive breast cancer.

Limitations of Use

Raloxifene is not approved for the treatment of existing invasive breast cancer, the reduction of the risk of breast cancer recurrence, or the reduction of the risk of non-invasive breast cancer.

Boxed Warning

The FDA requires a boxed warning for raloxifene due to serious safety concerns:

Blood Clots: There is an increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE). The risk is highest during the first four months of treatment.

Stroke: Clinical trials showed an increased risk of death due to stroke in postmenopausal women with coronary heart disease or those at high risk for major coronary events.

Question 12

What should I know about Raloxifene and cost?

Accepted Answer

Generic vs.

Brand Name

Raloxifene is available as a generic medication and under the brand name Evista. Generic drugs generally cost significantly less than their brand-name counterparts while providing the same therapeutic benefits.

Factors Affecting Price

Several factors can influence the out-of-pocket cost for this medication:

Insurance Coverage: Most insurance plans, including Medicare Part D, cover generic raloxifene, though copayments vary by plan.

Pharmacy Selection: Prices may differ between retail pharmacies, mail-order services, and specialty pharmacies.

Dosage and Quantity: The total cost will depend on the number of tablets prescribed, typically for a 30-day or 90-day supply.

Patients are encouraged to check with their insurance provider or pharmacist to determine the exact cost and explore potential savings programs or generic alternatives.

Raloxifene

📋Overview

What It's Used For

How It Works

Brand Names

Side Effects

Warnings & Precautions

Dosage & How to Take

Pregnancy & Breastfeeding

Forms & Strengths

FDA / Regulatory Status

Price Information

FAQ

📚References

Found an Error?

Raloxifene Price Comparison & Savings Options

Not Medical Advice

Hospitals.net Disclosure