Question 1

What is Welchol?

Accepted Answer

Welchol is a medication classified as a bile acid sequestrant. It works by binding to bile acids in the digestive tract, which prevents them from being reabsorbed into the bloodstream and helps the body lower cholesterol levels.

In addition to its role in managing cholesterol, this medication is used to help regulate blood sugar levels. It functions within the digestive system to support overall metabolic management.

Question 2

What is Welchol used for?

Accepted Answer

Welchol is used to treat primary hyperlipidemia and type 2 diabetes mellitus (as adjunct to diet and exercise).

Question 3

How does Welchol work?

Accepted Answer

Welchol belongs to a group of medications known as bile acid sequestrants. Its primary function is to lower low-density lipoprotein (LDL) cholesterol, often called bad cholesterol. The process works as follows:

Bile Acid Binding: The liver uses cholesterol to produce bile acids, which are released into the intestines to help digest fats.

Preventing Reabsorption: Under normal conditions, most bile acids are reabsorbed into the bloodstream to be used again. Welchol binds to these bile acids in the digestive tract, creating a substance that the body cannot absorb.

Elimination: The bound bile acids are removed from the body through bowel movements.

Cholesterol Depletion: Because the bile acids are being removed rather than recycled, the liver must produce more. To do this, the liver takes cholesterol out of the blood, which reduces the overall level of LDL cholesterol circulating in the body.

Welchol is also used to improve blood sugar control in adults with type 2 diabetes. While the medication is effective at lowering glucose levels, the exact way it achieves this is not entirely clear. It is believed that by interacting with bile acids in the intestines, the drug triggers certain signals that help the body manage blood sugar more effectively.

Welchol is not absorbed into the bloodstream; it stays within the digestive tract to perform its work before being passed out of the body.

Question 4

What are the active ingredients in Welchol?

Accepted Answer

The active ingredient in Welchol is colesevelam .

Question 5

What are the side effects of Welchol?

Accepted Answer

Common side effects of Welchol may include:

Constipation

Indigestion

Nausea

Always consult with a healthcare professional about potential side effects.

Question 6

What drug class is Welchol?

Accepted Answer

Welchol belongs to the bile acid sequestrant drug class.

Question 7

What is the dosage of Welchol and how do I take it?

Accepted Answer

General Instructions

Welchol should be taken with a meal and a full glass of water or another liquid. It is typically prescribed to be taken once or twice every day.

Tablets

When taking the tablet form of this medication, swallow the tablets whole. Do not crush, chew, or break them.

Oral Suspension

The powder form of Welchol must be mixed with liquid before consumption. Empty the packet into a glass and add water, fruit juice, or a diet soft drink. Stir the mixture thoroughly and drink it immediately. To make sure the entire dose is taken, add a little more liquid to the glass, swirl it, and drink the remaining contents.

Missed Dose

If a dose is missed, it should be taken as soon as it is remembered. If it is almost time for the next dose, skip the missed dose and return to the regular schedule. Do not take extra medicine to compensate for a missed dose.

Question 8

Is Welchol safe during pregnancy and breastfeeding?

Accepted Answer

Pregnancy

Welchol is not absorbed from the digestive tract into the bloodstream. Because the medication does not circulate throughout the body, it is not expected to reach the fetus or cause birth defects when used at recommended doses. However, there are no adequate and well-controlled studies of Welchol use in pregnant women.

One concern during pregnancy is that Welchol can interfere with the body's ability to absorb fat-soluble vitamins, including vitamins A, D, E, and K. These vitamins are important for the health of both the mother and the developing fetus. If you are pregnant or planning to become pregnant, discuss your nutritional needs and the potential risks and benefits of this medication with your healthcare provider.

Breastfeeding

Because Welchol is not absorbed into the mother's system, it is not expected to pass into breast milk. It is generally considered unlikely to pose a risk to a nursing infant. As with any medication, it is important to consult a healthcare professional before breastfeeding while taking Welchol to ensure it is appropriate for your specific situation.

Question 9

What forms and strengths does Welchol come in?

Accepted Answer

Oral Tablet

Welchol is provided as a solid tablet intended for oral use. These tablets are generally taken with food and a liquid.

Powder for Oral Suspension

This medication is also available in powder form, packaged in packets. The powder must be mixed thoroughly with a liquid—such as water, fruit juice, or diet soda—before it is consumed. Like the tablets, the suspension is typically taken with a meal.

Question 10

What is the FDA approval status of Welchol?

Accepted Answer

FDA Approval and Indications

Welchol (colesevelam hydrochloride) was first approved by the U.S. Food and Drug Administration (FDA) in 2000. It is currently approved for the following indications:

Primary Hyperlipidemia: To reduce elevated low-density lipoprotein cholesterol (LDL-C) in adults with primary hyperlipidemia and in children aged 10 to 17 years with heterozygous familial hypercholesterolemia, typically in combination with diet and exercise.

Type 2 Diabetes Mellitus: To improve glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise.

Regulatory Oversight

Welchol is not classified as a controlled substance. There are no FDA boxed warnings or Risk Evaluation and Mitigation Strategy (REMS) requirements associated with this medication. The FDA notes that Welchol has not been studied for the treatment of type 1 diabetes or diabetic ketoacidosis, and its impact on cardiovascular outcomes has not been established.

Question 11

What should I know about Welchol and cholesterol?

Accepted Answer

How Welchol Lowers Cholesterol

Welchol belongs to a class of medications known as bile acid sequestrants. It works by binding to bile acids in the intestines, which are substances the liver produces using cholesterol. By binding to these acids and preventing them from being reabsorbed into the body, Welchol forces the liver to use more cholesterol from the blood to create new bile acids. This process results in lower levels of "bad" LDL cholesterol circulating in the bloodstream.

Indications for Use

This medication is specifically used to manage cholesterol in the following populations:

Adults with primary hyperlipidemia (high blood cholesterol).

Children and adolescents aged 10 to 17 years with heterozygous familial hypercholesterolemia, a genetic condition that causes high cholesterol levels.

Welchol can be used as a standalone treatment or in combination with other cholesterol-lowering drugs, such as statins. When used with a statin, it can provide additional reduction in LDL cholesterol levels.

Effect on Triglycerides

While Welchol is effective at lowering LDL cholesterol, it is not used to treat high triglycerides. In some patients, the medication may actually cause triglyceride levels to increase. Because of this, healthcare providers typically monitor blood lipid levels, including triglycerides, before starting the medication and periodically during treatment.

Welchol

📋Overview

What It's Used For

How It Works

Side Effects

Warnings & Precautions

Dosage & How to Take

Pregnancy & Breastfeeding

Forms & Strengths

FDA / Regulatory Status

Cholesterol Information

FAQ

📚References

Found an Error?

Welchol Price Comparison & Savings Options

Not Medical Advice

Hospitals.net Disclosure