📋Overview

Hereditary spherocytosis occurs due to defects in the proteins that comprise the red blood cell membrane, causing cells to lose their typical biconcave disc shape and become spherical. These rigid cells, known as spherocytes, are often unable to pass through the narrow passages of the spleen, leading to their early breakdown.

This accelerated destruction of red blood cells can result in hemolytic anemia, as the body may struggle to replace the cells as quickly as they are removed. The condition is recognized as a common inherited form of anemia resulting from these specific structural cellular abnormalities.

Educational overview only. This page summarizes publicly available health information for general understanding and awareness. It does not provide medical advice, diagnosis, or treatment. For personalized guidance or care decisions, consult a qualified healthcare professional.

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Medical codes (for reference)

UMLS CUI: C0037889
ICD-10-CM
D58.0
MeSH
D013103
SNOMED CT (US)
55995005

Codes are provided for reference and interoperability. They are not a diagnosis.

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