Primary Immunodeficiency

📋Overview

These conditions, also known as inborn errors of immunity, occur when genetic factors impair the development or function of the immune response. This impairment can lead to an increased susceptibility to infections, autoimmune diseases, and certain malignancies.

The term describes a variety of congenital disorders where the body's natural defense mechanisms are compromised from birth. These intrinsic defects are distinct from secondary immune deficiencies that may arise from external causes or other underlying health conditions.