Subendocardial Sclerosis

📋Overview

Subendocardial sclerosis describes pathological changes where the subendocardial layer of the heart develops fibrous tissue, typically due to chronic ischemia. This condition is often associated with a persistent lack of oxygenated blood flow, leading to scarring beneath the endocardium.

Modern clinical practice often classifies these findings under ischemic cardiomyopathy or myocardial fibrosis secondary to coronary artery disease. The term is primarily used to characterize structural damage resulting from long-term heart muscle injury.